Towards Imaging Skin Cancer by Apertureless Scanning Near-field Optical Microscopy
نویسندگان
چکیده
Laser Scanning Microscopy Techniques such as Confocal Microscopy, Two Photon Excitation Microscopy, Second Harmonic Generation Microscopy or Fluorescence Lifetime Imaging have been successfully employed to date for imaging skin cancer. However, the resolution that such techniques can provide is limited by diffraction, which prevents accurately imaging (and differentiating) optical details sized below ~200nm, which could potentially advance our current understanding of skin cancer progression or causes. In this paper we present the results of our first efforts on imaging tissue samples relevant for skin cancer research at optical resolutions beyond the diffraction limit by using Apertureless Scanning Near-Field Optical Microscopy.
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